GAMBARAN NILAI SGOT DAN SGPT PASIEN TUBERKULOSIS PARU YANG DIRAWAT INAP DI RSUD ARIFIN ACHMAD PROVINSI RIAU TAHUN 2013

Widya Adriani, Zarfiardy Aksa Fauzi

Abstract


Abstract
Tuberculosis (TB) adalah suatu penyakit infeksi menular yang disebabkan
oleh kuman Mycobacterium tuberculosis.Tuberculosis ( TB ) is an infectious disease
caused by Mycobacterium tuberculosis. TB germs attack the organ is mostly the
lungs ( pulmonary TB ) , but also can affect almost every organ of the human body .
Morbidity and mortality from tuberculosis is a serious problem , especially due to the
incidence of side effects due to Anti Tuberculosis ( OAT ) . Side effects The most
serious OAT is hepatotoxic .
According to the American Association for the Study of Liver Disease (
AASLD ) , establishes that the parameters for determining the presence or absence of
liver damage is to look at the levels of serum glutamic Pyruric transaminase ( SGPT )
increased more than three times the upper limit of normal , and serum glutamic
oxaloacetic transaminase ( SGOT ) . The purpose of this study to describe the value
of AST and ALT in patients with pulmonary tuberculosis hospitalized in Arifin
Achmad Riau Province in 2014 by age , sex and determine the degree of
hepatotoxicity . This study will be conducted at the medical records of the District
General Hospital Arifin Achmad Riau Province in January 2015 .
The study sample as many as 69 people . The data collected is secondary
data obtained from medical records . The results showed that the largest age group
of patients with pulmonary tuberculosis were aged 40-49 years were 17 ( 24.63 % ) .
While the sex of pulmonary TB patients it was found that men were 36 people ( 52.17
% ) . Pulmonary TB patients who experienced hepatotoksitas based SGOT was 10
people ( 14.49 % ) . Pulmonary TB patients with hepatotoxicity based SGPT value is
7 ( 10.14 % ) .
pulmonary TB patients with hepatotoxicity based AST highest in the age
group 40-49 years are 4 people and hepatotoxicity based SGPT highest in the age
group 18-29 years is 3 people . pulmonary TB patients with hepatotoxicity based AST
same incidence between men and women respectively 5 people . Pulmonary TB
patients with hepatotoxicity based SGPT most suffered by men is 6 people , while
women only 1 person .
Keywords: Pulmonary tuberculosis , SGOT , SGPT

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