EVALUATION USAGE OF ANTIBIOTIC TO SEPSIS NEONATUS PATIENT IN RSUD ARIFIN ACHMAD PROVINCE RIAU

Abstract

ABSTRACT
Sepsis neonatus is systemic clinical syndrome usually accompanied with
bacteremia that needed prompt and proper antibiotic therapy. This study purpose
was evaluating usage of antibiotic to sepsis neonatus patient in RSUD Arifin Achmad
Province Riau. This study method was descriptive retrospective. Data sources were
taken from medical record of sepsis neonatus patient in RSUD Arifin Achmad
Province Riau period 1 January - 31 December 2015. Based on characteristic of
patient, neonatal sepsis mostly found on female 57,4%, low birth weight 57,8%, low
gestational age 66,2%, and pervaginum labor 52,9%. Blood culture time, found that
most culture more than 3 days 63,2%. Microorganism of cause mostly found
Coagulase Negative Staphylococci 35,3%. Usage of empirical antibiotics mostly
given 2 antibiotics 60,3%, type of antibiotic was aminoglycoside 42,1%, with
duration more than 72 hours 55,5%. Usage of definitive antibiotics mostly were not
given to sepsis neonatus patient 44,1%, while mostly they were given single antibiotic
30,9%, most used type of antibiotic were aminoglycoside 40% (20 of 60 antibiotics),
and duration less than 7 days 50% (30 of 60 antibiotics). Conclusion of this study
were duration of empiric antibiotics mostly given combination of two antibiotics with
duration more than 72 hours and empiric antibiotics were suitable with
microorganism that caused sepsis in RSUD Arifin Achmad 2015.
Key word : sepsis neonatus, empiric antibiotic, definitive antibiotic